In-Situ Silicone Oil Production Freeze Dryer

Engineered for formal pharmaceutical mass manufacturing and standardized batch lyophilization, the in-situ silicone oil production freeze dryer integrates exclusive heating and vacuum control technology. Different from conventional pilot lyophilizers, it focuses on production-grade stability, sterilization compatibility and full-process data traceability, fully matching clean workshop operation and pharmaceutical regulatory compliance standards.

Optimized Lyophilization Curve Algorithm

Adopting professional freeze-drying curve optimization control technology, the machine realizes full-stage parameter closed-loop regulation. It accurately modulates sample cooling speed throughout the pre-freezing phase, and synchronously adjusts shelf heating rate and internal vacuum degree during sublimation and desorption drying stages. The refined parameter linkage control avoids sample activity degradation and shortens overall lyophilization cycle to boost production capacity.

Optimized Gas Path System for High Dehydration Efficiency

Supported by specialized gas flow channel layout and precise gas pressure control logic, the industrial-grade gas circuit delivers stable air circulation. It strengthens cold trap moisture condensation and water vapor capture capability, removes residual moisture efficiently, and maintains consistent drying efficiency amid long-term continuous batch production.

Patented Dual-seal Steam Sterilization Structure

Featured with proprietary dual-seal technology combining movable and fixed cavity door sealing components. The collaborative sealing structure enables synchronous sterilization of fixed silicone rubber seals during steam disinfection, eliminating dead corners of sterilization. It prevents bacterial contamination and sealing aging risks, realizing full-chamber sterile production and satisfying strict GMP sanitation standards.

Adaptive Vacuum Regulation to Avoid Sample Damage

Equipped with dynamic vacuum adaptive adjustment function. The system intelligently modulates real-time vacuum pressure according to sample characteristics, which effectively suppresses material foaming and vial blowout caused by volatile active substances. It reduces product scrapping rate while stabilizing overall drying progress for repeatable batch production.

Stable Modular Industrial Control System

Combined with industrial embedded touchscreen and exclusive modular controller, the whole control system achieves anti-interference operation, ultra-high control accuracy and long-running operational stability. It supports mass storage of diversified lyophilization process recipes, and allows real-time parameter modification during ongoing production, greatly accelerating pharmaceutical process iteration and optimization.

Production-oriented Intelligent Monitoring & GMP Traceability

This production lyophilizer is built with dedicated industrial functions including automatic freeze-drying endpoint judgment, remote data monitoring via industrial host computer and mobile terminal. Dual switchable operation modes fit the whole industrial chain: manual mode for new pharmaceutical process research and formula verification, and automatic mode for large-scale continuous mass production.

The built-in data storage module continuously archives operating records, lyophilization curves and equipment alarm logs for several years. It supports one-click data retrieval, equipment fault diagnosis and production status tracking. Configurable multi-level user accounts and password protection enable refined role-based access control, preventing unauthorized operation and data tampering, which fully meets pharmaceutical GMP audit requirements.

1. Sterile Injectable Drug Mass Manufacturing & CDMO Contract Production

Specially designed for full-line vial lyophilization in Class A/B clean pharmaceutical workshops. It handles large-batch sterile injectables including polypeptide APIs, monoclonal antibody preparations, oncological lyophilized injections and lyophilized antibiotics. Dynamic adaptive vacuum regulation eliminates vial foaming and blowout risks during continuous shift production. The integrated steam sterilizable dual-seal system removes sterilization dead zones to meet aseptic filling linkage standards for CDMO pharmaceutical outsourcing factories.

2. Viral Vaccine & Biologics Large-Scale Industrialization

Suitable for industrial production of inactivated vaccines, mRNA vaccine intermediates and live bacterial probiotic bulk preparations. The full-stage curve optimization algorithm precisely controls pre-freezing cooling rate and sublimation heating speed to stabilize fragile viral and bacterial activity across thousands of vials per batch. Long-term multi-year data logging, remote mobile monitoring and role-based permission management fully satisfy drug registration and regulatory batch audit requirements for biotech industrial parks.

3. Medical In-Vitro Diagnostic Reagent Industrial Mass Production

Matching automated diagnostic reagent assembly lines for bulk lyophilized detection kits, enzyme standard substances and antigen-antibody raw materials. High-flatness, pressure-resistant production trays deliver uniform heat conduction to avoid inconsistent reagent activity. Manual/automatic dual modes support new reagent process validation and uninterrupted mass production switching; reserved industrial communication interfaces enable seamless docking with automatic filling, capping and packaging equipment.

4. High-End Sterile Botanical Monomer Raw Material Factory Production

For standardized large-batch deep processing of high-value herbal monomer extracts, ginsenoside raw powder and plant active sterile extracts. The optimized gas flow system enhances moisture capture efficiency to shorten production cycles, while inert gas filling function prevents oxidation of easily degraded botanical active ingredients post-drying. Unlike small pilot equipment, it supports non-stop multi-shift production for herbal pharmaceutical factories with strict microbial control standards.

5. Medical Biodegradable Material & Special Biomedical Material Industrial Preparation

Applied for batch lyophilization of water-sensitive porous medical scaffolds, collagen biomembrane raw materials and injectable sustained-release carrier materials. Precise closed-loop temperature control avoids thermal decomposition of fragile polymer structures. Endpoint automatic drying judgment function reduces manual inspection labor, and complete historical curve/alarm log storage provides full traceability for medical device registration and factory quality management system inspection.