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Stirring operations are applied across an extremely wide range of industries. Even within the biomanufacturing sector alone, beyond upstream fermentation and cell culture, stirring is extensively used in solution preparation, downstream purification, pre-harvest processing, formulation manufacturing, and environmental treatment.
In practical spray drying operations, collection efficiency is one of the core metrics for evaluating equipment performance and process compatibility. It is defined as the ratio of the mass of dry powder actually collected to the theoretical powder mass calculated from the total solid content of the feed liquid. For laboratory-scale spray dryers, the target collection efficiency is generally required to reach 85% to 95% or higher.
Optical pigments are a class of functional pigments with unique optical structures. Thanks to their colour-shifting properties, high gloss and excellent weather resistance, they are widely used in high-end cosmetics, automotive coatings, and printing and packaging. Their core value lies in the unique visual effects they produce through the refraction and reflection of light, whilst the dispersion state of the particles directly influences the product’s final optical performance and stability.
In industrial fermentation for biopharmaceutical production, process stability, batch-to-batch reproducibility, and high product yield are core quality control objectives.
Original Author: Sai'ao Jun | Cell Culture | May 19, 2026, 20:08 | Shanghai
In the biopharmaceutical industry, Chinese Hamster Ovary （ CHO ） cells serve as the core "cell factories" for the production of recombinant protein drugs, especially monoclonal antibodies.
Protein therapeutics (monoclonal antibodies, fusion proteins, ADCs, etc.) have become core treatments for major diseases like cancer and autoimmune disorders due to their precision targeting.
Extracellular vesicles (EVs) hold immense potential as drug delivery platforms due to their unique role in intercellular communication. However, numerous limitations—including low drug encapsulation efficiency and difficulties in scaling traditional methods—pose challenges for the clinical translation of EVs as delivery vehicles.
Given the sensitivity of animal cells, monitoring and controlling production process parameters is a mandatory task requiring meticulous attention. Monitoring must be systematically organized and should provide clear, unambiguous results.
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