Single-Use Direct-Axis Stirred Bioreactor

Product Introduction:

Excellent axial flow mixing and mass transfer performance.

High-quality components for stable system operation.

Modular design with customized support and easy operation.

Three-level authority, audit trail and transferable electronic data reports.

Intuitive touchscreen software with clear feedback logic.

Flexible macro/micro bubble aeration & complete FAT, SAT, IQ/OQ services.

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The TOR Vertical‑Agitator Bioreactor Series is designed based on conventional mixing principles. Featuring low‑shear, vertical‑axis impellers, it combines robust mixing performance with the significant advantage of eliminating cleaning, sterilization and validation steps.

Integrating hardware, software and single‑use consumables, it forms an efficient, user‑friendly cell culture platform that optimizes cell growth, viability and metabolic profiles. The system supports a scalable volume range from 50L to 2000L, accommodating diverse bioprocess needs.

The single-use, vertical-axis stirred bioreactor has been developed and tested for mammalian cell culture. It is suitable for use in the biopharmaceutical sector, including antibodies, vaccines, gene therapy and cell therapy. Typical applications include:

Suspension cell culture

Adherent cell culture on microcarriers

Process development

Process scale-up

Pilot-scale production

Seed expansion

GMP production

TECHNICAL PARAMETERS

Specification	50L	200L	500L	1000L	2000L
Working volume (L)	12.5-50	50-200	125-500	250-1000	500-2000
Range of speed (rpm)	0-240	0-150	0-110	0-90	0-70
Accuracy of rotational speed control	±2 rpm
Temperature control	Control range: Room temperature ~ 42 °C; control accuracy: ± 0.2 °C
pH control*	*Digital intelligent electrode, control range: 0-12; control accuracy: ± 0.02
pH control*	Single-use optical fiber electrode, control range: 5.5-8.5; control accuracy: ± 0.1
DO control*	*Optical intelligent electrode, control range: 0-100% Air saturation, control accuracy ± 5%
DO control*	Single-use optical fiber electrode, control range 0-100% Air saturation, control accuracy: ± 5%
Mass flow controller MFC*	Accuracy: ± 2% FS; resolution: 1ml/min
Weight	Accuracy: C3, resolution: 0.1kg
Peristaltic pump	Speed: 0-400 rpm; flow range: 0-1200ml/min
Pressure protection	Measuring range: 0-25kpa; accuracy 0.25/FS
Offgas heating control	Control range: Room temperature ~ 60°C; control accuracy ± 0.5 °C
Overall dimensions of the reactor (L×W×H, mm)	8536701940	80010001115	126410022306	/	172816583868
Overall dimensions of the control cabinet (L×W×H, mm)	5386291630	5386291630	5386291630	5386291630	5386291630
Power of the control cabinet (KW)	2	2	2.6	2.6	17
Size of TCU	450550650	550650970	6506701250		7606501605
Power of TCU (KW)	2	5	7	10	20
Weight (Kg)	300	470	620	/	2620

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Single-Use Direct-Axis Stirred Bioreactor